Presented Supportive Preclinical Data for Lead Candidate GT-02287 at Recent Medical Meetings Further Validating Therapeutic Potential and Clinical Study in Parkinson’s Disease and Gaucher’s Disease.
$34.34 Million in Cash as of March 31, 2022, Provides Runway into Second half of 2023 and a Strong Cash Position to Transition the Company’s Lead Program into Clinical Trials
Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a biotechnology company transforming drug discovery with its proprietary computational discovery platform identifying novel allosteric binding sites and creating small molecule treatments, today announced its financial results for the first quarter ended March 31, 2022, and highlighted recent corporate accomplishments.
“This has been a productive quarter for Gain, as we continued to demonstrate the broad reaching potential of our SEE-Tx platform,” said Eric Richman, Chief Executive Officer of Gain Therapeutics. “Our strategy of exploring previously unidentified allosteric binding sites and targeting them for therapeutic benefit has proved promising. Our STAR’s appear to correct enzyme misfolding, restore function and eliminate toxic substrate buildup, providing hope for patients suffering from neurodegenerative and lysosomal disorders. We are encouraged by recently presented data and look forward to the year ahead as we progress our programs in Parkinson’s and in Gaucher disease into the clinic.”
Business and Recent Developments
Upcoming 2022 Milestones
Financial Results
For the first quarter ended March 31, 2022, as compared to the first quarter ended March 31, 2021:
Revenues were $45 thousand for the three-month period ended March 31, 2022, compared $5 thousand for the same period of 2021. The increase was primarily attributable to development services on the first target development program identified under the Zentalis Pharmaceuticals collaboration agreement.
Research and development expenses of $1,556 thousand for the three-month period ended March 31, 2022 compared to $1,422 thousand for the same period of 2021, an increase of $134 thousand. The increase in research and development expenses for the three months ended March 31, 2022 was primarily attributable to increases in personnel-related costs resulting from an increase in employee headcount and non-cash stock-based compensation that amounted to $114 thousand and $63 thousand as of March 31, 2022 and 2021, respectively, offset by lower outside services.
General and administrative expenses were $1,777 thousand for the three-month period ended March 31, 2022 compared to $1,051 thousand for the same period of 2021, an increase of $726 thousand. The increase in general and administrative expenses for the three months ended March 31, 2022 was primarily attributable to increase in expenses for corporate matters, investor relations, information technology as we continue to expand our business and build management infrastructure and increases in personnel-related costs resulting from an increase in employee headcount and non-cash stock-based compensation expenses that amounted to $192 thousand and $48 thousand as of March 31, 2022 and 2021, respectively.
As a result of the above, net loss was $3,273 thousand, or $0.28 per share basic and diluted, for the three-month period ended March 31, 2022, compared to $2,540 thousand or $0.50 per share basic and diluted, for the same period of 2021.
Cash and cash equivalents were $34.34 million as of March 31, 2022 compared to $36.88 million at December 31, 2021.
GAIN THERAPEUTICS, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(unaudited)
March 31, | December 31, | ||||||
2022 | 2021 | ||||||
Assets | |||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 34,338,585 | $ | 36,880,673 | |||
Tax credits | 121,142 | 113,586 | |||||
Prepaid expenses and other current assets | 1,932,286 | 727,785 | |||||
Total current assets | $ | 36,392,013 | $ | 37,722,044 | |||
Non-current assets: | |||||||
Property and equipment, net | 106,725 | 105,986 | |||||
Internal-use software | 220,510 | 202,609 | |||||
Operating lease - right of use assets | 831,229 | 901,042 | |||||
Restricted cash | 30,860 | 31,279 | |||||
Long-term deposits | 17,205 | 22,111 | |||||
Total non-current assets | 1,206,529 | 1,263,027 | |||||
Total assets | $ | 37,598,542 | $ | 38,985,071 | |||
Liabilities and stockholder's equity | |||||||
Current liabilities: | |||||||
Accounts payable | $ | 2,118,443 | $ | 560,479 | |||
Operating lease liability - current | 222,467 | 219,137 | |||||
Other current liabilities | 1,587,411 | 1,402,600 | |||||
Deferred income | 202,034 | 266,504 | |||||
Loans - short term | 86,624 | 103,826 | |||||
Total current liabilities | 4,216,979 | 2,552,546 | |||||
Non-current liabilities: | |||||||
Defined benefit pension plan | 367,434 | 329,458 | |||||
Operating lease liability - non-current | 625,449 | 695,053 | |||||
Loans - long term | 560,889 | 590,468 | |||||
Total non-current liabilities | 1,553,772 | 1,614,979 | |||||
Total liabilities | $ | 5,770,751 | $ | 4,167,525 | |||
Stockholders’ equity | |||||||
Preferred stock, $0.0001 par value; 10,000,000 shares authorized; 0 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively | |||||||
Common stock, $0.0001 par value: 50,000,000 shares authorized; 11,883,368 issued and outstanding as of March 31, 2022 and December 31, 2021, respectively | 1,189 | 1,189 | |||||
Additional paid-in capital | 56,139,006 | 55,832,461 | |||||
Accumulated other comprehensive loss | (114,302 | ) | (90,645 | ) | |||
Accumulated deficit | (20,925,459 | ) | (7,034,853 | ) | |||
Loss of the period | (3,272,643 | ) | (13,890,606 | ) | |||
Total stockholders’ equity | 31,827,791 | 34,817,546 | |||||
Total liabilities and stockholders’ equity | $ | 37,598,542 | $ | 38,985,071 |
GAIN THERAPEUTICS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(unaudited)
Three Months Ended March 31, | |||||||
2022 | 2021 | ||||||
Revenues: | |||||||
Collaboration revenues | 37,538 | — | |||||
Other income | 7,468 | 5,269 | |||||
Total revenues | $ | 45,006 | $ | 5,269 | |||
Operating expenses: | |||||||
Research and development | (1,556,440 | ) | (1,421,509 | ) | |||
General and administrative | (1,777,043 | ) | (1,050,675 | ) | |||
Total operating expenses | $ | (3,333,483 | ) | $ | (2,472,184 | ) | |
Loss from operations | $ | (3,288,477 | ) | $ | (2,466,915 | ) | |
Other income (expense): | |||||||
Interest (expense)/income, net | (1,651 | ) | 1,408 | ||||
Foreign exchange loss, net | 19,162 | 18,539 | |||||
Loss before income tax | $ | (3,270,966 | ) | $ | (2,446,968 | ) | |
Income tax | (1,677 | ) | (3,479 | ) | |||
Net loss | $ | (3,272,643 | ) | $ | (2,450,447 | ) | |
Net loss per shares: | |||||||
Net loss per share attributable to common stockholders - basic and diluted | $ | (0.28 | ) | $ | (0.50 | ) | |
Weighted average common shares - basic and diluted | 11,883,368 | 4,868,915 |
About Gain Therapeutics, Inc.
Gain Therapeutics, Inc. is transforming drug discovery with its proprietary computational discovery platform identifying novel allosteric binding sites and creating small molecule treatments to address unmet medical needs. The ability to identify never-seen-before allosteric targets on proteins involved in diseases across the full spectrum of therapeutic areas provides opportunities for a range of drug-protein interactions, including protein stabilization, protein destabilization, targeted protein degradation, allosteric inhibition and allosteric activation. Gain’s pipeline spans neurodegenerative diseases, lysosomal storage disorders, metabolic diseases and oncology. Gain’s lead program in Parkinson’s disease has been awarded funding support from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and The Silverstein Foundation for Parkinson’s with GBA, as well as from the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and Innosuisse. For more information, please visit https://www.gaintherapeutics.com.
Cautionary Note Regarding Forward-Looking Statements
This press release contains "forward-looking statements." In some cases, you can identify these statements by forward-looking words such as "may," "might," "will," "should," "expect," "plan," "anticipate," "believe," "estimate," "predict," "potential" or "continue," the negative of these terms and other comparable terminology. These statements are not historical facts but instead represent the Company's belief regarding future results, many of which, by their nature, are inherently uncertain and outside the Company's control. It is possible that actual results, including with respect to any financial forecast or the possibility of any future regulatory approval or filing, may differ materially from those anticipated in these forward-looking statements due to a number of factors, including but not limited to, risks detailed in the Company’s Annual Report on Form 10-K for the year ended December 31, 2021, as filed with the Securities and Exchange Commission on March 25, 2022, as well as other documents that may be filed by the Company from time to time. New risks and uncertainties arise over time, and it is not possible for us to predict all such factors or how they may affect us. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. We are under no duty to update any of these forward-looking statements after the date of this earnings release to conform these statements to actual results or revised expectations. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this earnings release.
Investor & Media Contact:
Noor Pahlavi
Argot Partners
(212) 600-1902
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Market Cap: | US$56.700M |
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